Megyn Kelly questions Applegate's distress over changed MS diagnosis

Applegate says her symptoms have not improved, while viewers focus on what losing an explanation for illness can mean.

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Megyn Kelly Story of October 21, 2026Trari Newsroom

Why this story? The video opened at a pace of 306,254 views a day, 7 times a normal first day on this channel (43,854).

Megyn Kelly Reacts to Stunning Christina Applegate Announcement Revealing She NEVER Actually Had MS

The explanation mattered to her. In the podcast audio Megyn Kelly plays, Christina Applegate says being told she does not have multiple sclerosis has left her distressed, not relieved, because she still feels unwell.

Applegate recounts her doctor taking her off infusions and monitoring her B cells before telling her she does not have MS. Speaking to her MeSsy co-host Jamie-Lynn Sigler, she explains why that news did not feel like an improvement: "I haven't gotten better, Jamie. If anything, I've gotten worse in some ways."

Kelly responds by criticizing celebrities who center their identities on medical diagnoses. "And she's crying because she doesn't have MS," she says later in the Short.

That contrast is also the central subject of the comments. Viewers discuss the difference between receiving good news and losing an explanation for continuing symptoms. Several describe their own long searches for diagnoses; others ask Kelly to reconsider her interpretation of Applegate's distress.

The clip drew roughly 150,000 views in eight hours, already well beyond Kelly's usual full-day Shorts audience. Its comment section was also many times busier than a typical first day, with the discussion returning to Applegate's explanation: her condition has not improved, and she no longer has the answer she thought she had.

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